Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds
US7429616B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jul 15, 2005 |
| Grant date | Sep 30, 2008 |
| Priority date | — |
| Expiry date | Mar 22, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the synthesis and complete stereochemical assignments of cytotoxic compounds such as compound 28-a and its stereoisomers:The invention further provides processes for making the compounds, their synthetic intermediates, and for methods of using the compounds and their pharmaceutical compositions for the treatment of neoplastic diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.