Method for identification of t-cell epitopes and use for preparing molecules with reduced immunogenicity
US7430476B2 · kind B2 · utility
13Cited by
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5Claims
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Assignee
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Key dates
| Filing date | Feb 18, 2002 |
| Grant date | Sep 30, 2008 |
| Priority date | — |
| Expiry date | Apr 1, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B20/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method biological compounds can be generated which have a no or at least a reduced immunogenicity when exposed to the immune system of a given species and compared with the relevant non-modified entity. Thus the invention relates also to novel biological molecules, especially proteins and antibodies, obtained by the method according to the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.