Plant virus coat fusion proteins with GDF8 epitopes and vaccines thereof

US7432079B2 · kind B2 · utility

Assignee

• Schering-Plough Animal Health Corporation · US

Inventors

• David E. Junker · San Diego, US
• Mark D. Cochran · Carlsbad, US
• Mark Smith · Venetia, US
• Kenneth Palmer · Vacaville, US
• Gregory Pogue · Vacaville, US

Key dates

• Filing date: Dec 21, 2005
• Grant date: Oct 7, 2008
• Expiry date: Mar 17, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2770/00043
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a fusion protein comprising a plant virus coat protein and a GDF8 peptide domain, or antigenic fragment of the GDF8 peptide domain. Plant virus vectors expressing the fusion protein and methods of using these vectors are also provided.