Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US7432305B2 · kind B2 · utility
48Cited by
62References
21Claims
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Key dates
| Filing date | Sep 15, 2006 |
| Grant date | Oct 7, 2008 |
| Priority date | — |
| Expiry date | Sep 15, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C50/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), or Kearns-Sayre Syndrome (KSS) are disclosed, as well as compounds useful in the methods of the invention. Energy biomarkers useful in assessing the metabolic state of a subject and the efficacy of treatment are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.