Methods for producing ex vivo models for inflammatory disease and uses thereof
US7435548B2 · kind B2 · utility
0Cited by
5References
4Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 16, 2007 |
| Grant date | Oct 14, 2008 |
| Priority date | — |
| Expiry date | Jul 16, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to methods for inducing a pro-asthma/pro-inflammatory like state in a resident tissue cell, comprising contacting the cell with one or more cytokines, e.g., IL-β, TNFα or both. Methods are also disclosed for identifying genes that regulate responses to anti-inflammatory drugs, to methods for drug screening, and to methods for identifying genes that correlate with various pro-asthma/pro-inflammatory disease phenotypes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.