Use of ionic liquids for fabrication of polynucleotide arrays
US7435810B2 · kind B2 · utility
62Cited by
7References
28Claims
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Key dates
| Filing date | Dec 22, 2004 |
| Grant date | Oct 14, 2008 |
| Priority date | — |
| Expiry date | Aug 3, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/54
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of fabricating polynucleotide arrays includes dissolving a nucleotide monomer, oligonucleotide, or polynucleotide in a solvent containing ionic liquid and depositing the resulting solution on an array substrate. The method has particular application to fabrication of an addressable array of polynucleotides on a substrate that carries substrate bound moieties each with a hydroxyl group. The process may be repeated at specific locations on the array to elongate the polynucleotide deposited on the array.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.