Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
US7435833B2 · kind B2 · utility
13Cited by
2References
20Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 5, 2007 |
| Grant date | Oct 14, 2008 |
| Priority date | — |
| Expiry date | Apr 5, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of formula (I):or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof. Methods of inhibiting 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. Methods of treating non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.