Patent · US Expired

Dry granulated formulations of azithromycin

US7438924B2 · kind B2 · utility

1Cited by
10References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 31, 2003
Grant dateOct 21, 2008
Priority date
Expiry dateJun 12, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P33/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention relates to a pharmaceutical formulation, in the form of a tablet, sachet or powder for suspension dosage form, which comprises dry granulated particles of a non-dihydrate form of azithromycin and, optionally, one or more pharmaceutically acceptable excipients. Preferably, the pharmaceutical formulation is a tablet containing between about 40%, by weight, to about 90%, by weight, non-dihydrate azithromycin.More preferably, the pharmaceutical formulation contains non-dihydrate azithromycin selected from the forms B, D, E, F, G, H, J, M, N, O, P, Q, R, or mixtures thereof.Even more preferably, the invention relates to a pharmaceutical formulation wherein the dosage of azithromycin is 250 mgA, 500 mgA, 600 mgA or 1000 mgA.The present invention further relates to a dry granulated azithromycin particle, comprising a form of azithromycin, selected from forms D, E, F, G, H, J, M, N, O, P, Q, R and mixtures of non-dihydrate forms, and at least one pharmaceutically acceptable excipient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.