Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV)
US7439066B2 · kind B2 · utility
1Cited by
13References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 7, 2006 |
| Grant date | Oct 21, 2008 |
| Priority date | — |
| Expiry date | Nov 7, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/6072
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel pseudotyped retroviral vectors that can transduce human and other cells. Vectors are provided that are packaged efficiently in packaging cells and cell lines to generate high titer recombinant virus stocks expressing novel envelope glycoproteins. The present invention further relates to compositions for gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.