Process for the preparation of biphosphonic derivatives
US7439385B2 · kind B2 · utility
9Cited by
3References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 2006 |
| Grant date | Oct 21, 2008 |
| Priority date | — |
| Expiry date | May 31, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6561
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a novel process for preparation of bisphosphonic acid derivatives or pharmaceutical acceptable salt thereof, by reacting carboxylic acid having structural formula (II) with phosphorous acid and a halophosphorous compound, wherein halophosphorous compound is selected from the group comprising of PCl3, PCl5, POCl3, PBr3, POBr3, and PBr5 in presence of diphenyl ether.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.