KCNQ2-15 potassium channel
US7442519B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jun 20, 2003 |
| Grant date | Oct 28, 2008 |
| Priority date | — |
| Expiry date | Aug 6, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/304
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention encompasses polypeptides and polynucleotides of three novel bipolar disorder-associated potassium channel polypeptides, KCNQ2-15bx, KCNQ2-15by and KCNQ2-15bz. The invention further relates to the use of potassium channels comprising KCNQ2 subunits for screening for modulators thereof, the use of these modulators for treating mental disorders such as bipolar disorder, schizophrenia and depression, and drugs comprising these modulators. The invention also discloses biallelic markers located in the KCNQ2 gene and their use for diagnosing mental disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.