Amlodipine gentisate and a method of its preparation
US7442714B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Dec 15, 2004 |
| Grant date | Oct 28, 2008 |
| Priority date | — |
| Expiry date | Dec 15, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.