Polymorphic forms of sertraline hydrochloride
US7442838B2 · kind B2 · utility
11Cited by
7References
9Claims
0Family size
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Key dates
| Filing date | Apr 8, 2005 |
| Grant date | Oct 28, 2008 |
| Priority date | — |
| Expiry date | Jun 30, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Sertraline hydrochloride polymorphic form II is conveniently prepared by adding hydrogen chloride to solution of sertraline free amine in a ketone. In preferred processes, the solution of sertraline free amine seeded with some crystals of polymorphic form II and/or the solution is heated before addition of the hydrogen chloride.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.