Support for tissue regeneration and process for producing the same
US7445793B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 9, 2003 |
| Grant date | Nov 4, 2008 |
| Priority date | — |
| Expiry date | Sep 3, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides a scaffold in which cells can be stably retained and grafted in a uniform distribution state in the culture, preferable proliferation ability and viability can be secured, and particularly in the case of cartilage, fixation treatment such as suture can be carried out in the transplantation into affected parts after the culture, and the mechanical strength is provided sustainable for (weighted) compression at the initial stage of transplantation.The present invention relates to a 3-dimensional porous scaffold for tissue regeneration Further, the invention relates to the above 3-dimensional porous scaffold in which seeding properties of cells are improved by a pore enlargement treatment of one side face by a separation operation, a salt elution operation of a surface part, or a combination of these operations. It becomes possible to produce a 3-dimensional cell combination having excellent degree of tissue formation and medical treatment effect by seeding a cell or precursor cell derived from a tissue in this scaffold, and culturing them in an artificial environment and/or the living body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.