Patent · US Active

Wortmannin analogs and methods of using same in combination with chemotherapeutic agents

US7446124B2 · kind B2 · utility

3Cited by
6References
25Claims
0Family size

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Key dates

Filing dateJul 11, 2005
Grant dateNov 4, 2008
Priority date
Expiry dateJul 28, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/94
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.