Method for making nicotine hapten
US7446205B2 · kind B2 · utility
3Cited by
1References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 16, 2006 |
| Grant date | Nov 4, 2008 |
| Priority date | — |
| Expiry date | Jan 12, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A high yielding and short process for preparing the 3′-aminomethylnicotine hapten of general formula Ipermits the isolation of the hapten in very pure quantities. The process can be adapted for the synthesis of a single stereoisomer or mixtures of stereoisomers, such as the stereoisomers trans-Ia and trans-Ib:Compounds of general formula I are useful for the preparation of hapten-carrier conjugates in the treatment of nicotine addiction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.