Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
US7446213B2 · kind B2 · utility
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Key dates
| Filing date | Mar 7, 2006 |
| Grant date | Nov 4, 2008 |
| Priority date | — |
| Expiry date | Jun 3, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6825
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel methods allowing for the simple optical detection and electrochemical detection of doubled-straded oligonucleotides are disclosed. The methods are rapid, selective and versatile. Advantageously, they do not require any chemical reaction on the probes or on the analytes since they are based on different electrostatic interactions between cationic poly(3-alkoxy-4-methylthiophene) derivatives and single-stranded or doubled-stranded (hybridized) oligonucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.