Generation of multiply charged ions for tandem mass spectrometry
US7446312B2 · kind B2 · utility
7Cited by
1References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 24, 2006 |
| Grant date | Nov 4, 2008 |
| Priority date | — |
| Expiry date | May 2, 2027 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/0077
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
Multiply-charged ions are generated from singly-charged ions of analyte substances. The singly-charged ions, which are supplied by many types of ion sources, are accelerated, together with donor ions of substances which have only a very low proton affinity, into a reaction cell. In the reaction cell, protons are transferred from the donor ions to the analyte ions to protonate the analyte ions and increase the ion charge. The multiply-charged analyte ions are subsequently fragmented by a variety of techniques and mass analyzed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.