Molecular cardiotoxicology modeling
US7447594B2 · kind B2 · utility
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17References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 8, 2003 |
| Grant date | Nov 4, 2008 |
| Priority date | — |
| Expiry date | Apr 17, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known cardiotoxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.