Composition, vessel, dry powder inhalation system, and related methods for transpulmonary administration
US7448379B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2002 |
| Grant date | Nov 11, 2008 |
| Priority date | — |
| Expiry date | Nov 5, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/075
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-powder-form freeze-dried composition for transpulmonary administration has a disintegration index greater than or equal to 0.015 and contains at least one active ingredient. The composition becomes fine particles upon receiving air impact at an air speed greater than or equal to 1 meter/second and an air flow rate greater than or equal to 17 milliliters/second. The fine particles have a mean particle diameter less than or equal to 1×10−5 meters and/or a fine particle fraction greater than or equal to 10%. A method of making the composition, a vessel containing the composition, a method of administering the composition, a dry powder inhalation system for transpulmonary administration, and a method of transpulmonary administration are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.