Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
US7449300B2 · kind B2 · utility
38Cited by
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11Claims
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Key dates
| Filing date | Nov 21, 2003 |
| Grant date | Nov 11, 2008 |
| Priority date | — |
| Expiry date | Aug 8, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods of removing B7-H1-specific antibodies from a body fluid (e.g., blood), methods of diagnosing and treating diseases and pathological conditions mediated by activated T cells, methods for screening for compounds that inhibit binding of a B7-H1-specific antibody to B7-H1, and methods of designing compounds that inhibit binding of a B7-H1-specific antibody to B7-H1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.