Tri-substituted ureas as cytokine inhibitors
US7449474B2 · kind B2 · utility
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13Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 21, 2005 |
| Grant date | Nov 11, 2008 |
| Priority date | — |
| Expiry date | Nov 8, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.