Patent · US Expired

Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors

US7449482B2 · kind B2 · utility

16Cited by
18References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 28, 2004
Grant dateNov 11, 2008
Priority date
Expiry dateOct 26, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.