Diagnosis of mild osteoarthritis by determination of TNFAIP6 and TGFBI RNA levels
US7452667B2 · kind B2 · utility
17Cited by
0References
1Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 12, 2003 |
| Grant date | Nov 18, 2008 |
| Priority date | — |
| Expiry date | Apr 15, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to the identification and selection of sequences which demonstrate particular advantage in identifying individuals having osteoarthritis (OA). The invention also provides a selection of sequences particularly useful in diagnosing the degree of advancement of osteoarthritis of an individual and in the identification of novel therapeutic targets for OA. The invention further provides for the use of these sequences as a tool to diagnose disease progression and to monitor the efficacy of therapeutic regimens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.