T1R1 receptor binding assays for identification of taste modulators
US7452685B2 · kind B2 · utility
56Cited by
3References
37Claims
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Key dates
| Filing date | Dec 1, 2003 |
| Grant date | Nov 18, 2008 |
| Priority date | — |
| Expiry date | Jun 20, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Binding assays for identifying components that modulate human T1R1 polypeptide-associated taste are disclosed. These assays detect the specific binding of compounds to a human T1R1 polypeptide or the modulation of the specific binding of another compound that specifically binds human T1R1 polypeptide. The binding assays may include the use of detectable labels, e.g., radionuclides, enxymes, fluorophores, and the like. Compounds identified in these binding assays have potential application as T1R1 taste modulators and can be used as additives in compositions for human or animal consumption.
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