Terminal phosphate blocked nucleoside polyphosphates
US7452698B2 · kind B2 · utility
62Cited by
11References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 2007 |
| Grant date | Nov 18, 2008 |
| Priority date | — |
| Expiry date | Jul 24, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6851
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention describes terminal phosphate blocked nucleoside polyphosphates that are stable at high temperature and their use in nucleic acid amplification and analysis. Current invention further describes charge modified terminal phosphate blocked nucleoside polyphosphates for improved incorporation and direct loading of nucleic acid sequencing reactions onto separating media.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.