Lipid-derivatized bisphosphonic acid

US7455856B2 · kind B2 · utility

Assignee

• MCS MICRO CARRIER SYSTEMS GMBH · DE

Inventors

• Wolfgang Greb · Dinslaken, DE
• Oleg Shyhskov · Bremen, DE
• Gerd-Volker Röschenthaler · Bremen, DE
• Verena Hengst · Mülheim an der Ruhr, DE

Key dates

• Filing date: Jan 24, 2005
• Grant date: Nov 25, 2008
• Expiry date: May 8, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C23F11/1676
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A bisphosphonic acid of the general formula (I)wherein R1 is H, OH, C1-C6 alkyl C1-C6 alkoxy, C1-C6 hydroxyalkyl, C1-C6 aminoalkyl, C1-C6 halogen alkyl as well as their physiologically compatible derivatives in particular salts and trimethyl silyl derivatives.