Patent · US Active

Electrochemical detection of nucleic acid sequences

US7455975B2 · kind B2 · utility

4Cited by

23References

23Claims

0Family size

Assignee

ESA Biosciences, Inc. · US

Inventors

Robert W. Henkens · Durham, US
John P. O'Daly · Carrboro, US
Marek Wojciechowski · Cary, US
Honghua Zhang · San Diego, US
Najih Naser · Cary, US
R. Michael Roe · Apex, US
Thomas N. Stewart · Durham, US
Deborah M. Thompson · Raleigh, US
Rebecca Sundseth · Durham, US
Steven E. Wegner · Chapel Hill, US

Key dates

Filing date	Jan 3, 2007
Grant date	Nov 25, 2008
Priority date	—
Expiry date	Jan 3, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.