Immunoreactive and immunotherapeutic molecules

US7455984B2 · kind B2 · utility

Assignee

• THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH · AU

Inventors

• Leonard Charles Harrison · Melbourne, AU
• Margo Honeyman · Melbourne, AU
• George Rudy · Melbourne, AU
• Andrew Mark Lew · Melbourne, AU

Key dates

• Filing date: Jan 7, 2002
• Grant date: Nov 25, 2008
• Expiry date: Jun 28, 2022

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S424/81
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with antibodies or T-cells in subjects having pre-clinical or clinical Insulin-Dependent Diabetes Mellitus (IDDM). These molecules are preferentially immunoreactive to T-cells in subjects having pre-clinical or clinical IDDM and are useful in the development of diagnostic, therapeutic and prophylactic agents for IDDM.