Macrocycles useful in the treatment of alzheimer's disease
US7456163B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Aug 19, 2005 |
| Grant date | Nov 25, 2008 |
| Priority date | — |
| Expiry date | Aug 19, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is macrocycles of the formula (X):for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.