Method for analysing macromolecules
US7459304B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 19, 2001 |
| Grant date | Dec 2, 2008 |
| Priority date | — |
| Expiry date | Aug 17, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/102
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a method for the analysis of macromolecules using a microarray on which a plurality of first at least partly different macromolecules are located in a known arrangement, wherein the microarray is arranged on a solid surface on which a region is defined whose wetting properties differ from the surrounding solid surface such that a liquid with a plurality of second macromolecules preferably stays thereon, the liquid with the second macromolecules is brought onto the solid surface and at least partly removed and the second macromolecules remaining after the removal process are detected in order to determine from the position which of the first macromolecules have formed a bond with second macromolecules. The invention further relates to a method wherein a surface wave is launched to the liquid to distribute and/or thoroughly mix the liquid on the microarray.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.