Process for preparing substituted 8-azabicyclo[3.2.1]octan-3-ols

US7459556B2 · kind B2 · utility

Assignee

• Schering-Plough Corporation · FR

Inventors

• Ingrid Mergelsberg · Mahwah, US
• Gerald Werne · Ketsch, DE

Key dates

• Filing date: Sep 13, 2005
• Grant date: Dec 2, 2008
• Expiry date: Oct 10, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/22
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for preparing substituted 8-azabicyclo[3.2.1]octan-3-ols having the structural formula Ior a pharmaceutically acceptable salt or solvate thereof, wherein R is benzyl, R5-benzyl, allyl, —C(O)R6, —C(O)OR8 or —CH(R7)2;