Prostate cancer treatment
US7462610B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 11, 2007 |
| Grant date | Dec 9, 2008 |
| Priority date | — |
| Expiry date | Aug 11, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J21/008
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The instant invention provides potent antiandrogen compounds, such as 3β-acetoxyandrost-1,5-diene-17-ethylene ketal and 3β-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.