Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy
US7462713B2 · kind B2 · utility
13Cited by
6References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 23, 2006 |
| Grant date | Dec 9, 2008 |
| Priority date | — |
| Expiry date | Jul 21, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R2, R3 and R4 are as defined in the specification)pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers. The current invention relates to the making and using of such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.