Determination of nucleic acid using electrocatalytic intercalators
US7462720B2 · kind B2 · utility
1Cited by
3References
34Claims
0Family size
Inventors
Key dates
| Filing date | Sep 2, 2004 |
| Grant date | Dec 9, 2008 |
| Priority date | — |
| Expiry date | Oct 22, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6825
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compositions and methods for electrochemical detection of nucleic acid are disclosed. The compositions comprise electrocatalytic intercalators that bind to double-stranded nucleic acid and oxidize nucleic acid. Methods of detecting nucleic acid in a sample comprise forming double-stranded nucleic acid that is bound by electrocatalytic intercalators wherein the intercalators catalyze oxidation of the nucleic acid at the surface of an electrode.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.