Chloromethylation of thiophene
US7462725B2 · kind B2 · utility
1Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 2002 |
| Grant date | Dec 9, 2008 |
| Priority date | — |
| Expiry date | Sep 29, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The process according to the invention relates to the preparation of 2-chloromethyl-thiophene of the formula (I). During this process thiophene is chloromethylated in the presence of one or more compounds containing keto group and optionally it is transformed into the compound of the formula (II). Compounds of formula (I) and (II) are intermediates of several pharmaceutically active ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.