Combined ambient desorption and ionization source for mass spectrometry
US7462824B2 · kind B2 · utility
14Cited by
0References
13Claims
0Family size
Inventor
Key dates
| Filing date | Apr 28, 2006 |
| Grant date | Dec 9, 2008 |
| Priority date | — |
| Expiry date | Jan 28, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
Combined desorption and ionization sources are provided to generate molecular ions form a sample disposed on a substrate surface. A heated gas-jet probe or heated solvent stream probe desorbs sample molecules into the gas phase. The desorbed sample molecules are ionized by reaction between the sample molecule and charged solvent droplets. The charged solvent droplets may be produced by electrospray probe or by a corona discharge. The combined desorption and ionization sources coupled by a vacuum interface to a mass spectrometer, where the sample molecule ions can be analyzed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.