Highly stable surface plasmon resonance plates, microarrays, and methods
US7463358B2 · kind B2 · utility
10Cited by
21References
45Claims
0Family size
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Key dates
| Filing date | Dec 6, 2005 |
| Grant date | Dec 9, 2008 |
| Priority date | — |
| Expiry date | May 28, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An article, process, and method for surface plasmon resonance plates are described. A substrate is covered with a thin metal film onto which a second thin metal film is deposited. The surface of the second thin metal film is converted to the metal oxide which is used to covalently bond organosilanes to the surface. Reactive organosilanes containing terminal bonding groups are arranged in a plurality of spots that are surrounded by inert organosilanes. Biomolecule attachment to the binding group is detected or measured from surface plasmon signals from the first thin metal film.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.