Methods of preventing or treating graft versus host reaction by administering an antibody or portion thereof that binds to AILIM
US7465445B2 · kind B2 · utility
20Cited by
9References
4Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 5, 2003 |
| Grant date | Dec 16, 2008 |
| Priority date | — |
| Expiry date | Oct 7, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antibody against AILIM (alternatively called JTT-1 antigen, JTT-2 antigen, ICOS and 8F4) was found to have a significant therapeutic effect on arthrosis, for example, rheumatoid arthritis and osteoarthritis, graft versus host disease, graft immune rejection, inflammation (hepatitis and inflammatory bowel diseases), diseased condition accompanied by the excessive production of an antibody against a foreign antigen triggered by immunological sensitization by the antigen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.