Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration
US7465558B2 · kind B2 · utility
4Cited by
4References
24Claims
0Family size
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Key dates
| Filing date | May 12, 2004 |
| Grant date | Dec 16, 2008 |
| Priority date | — |
| Expiry date | Sep 27, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/1048
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system and method for high throughput patch clamp measurements to study the effect of various chemicals on ion transfer channels is provided. One or more patch clamp configurations is established, each comprising a cell sealed to a pipette. The pipettes are affixed to a pipette fixture. The pipette fixture and a plate comprising one or more wells are relatively moved so that each cell is inside a well. Electrical properties of the cells are measured.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.