Regulation of genes via application of specific and selective electrical and electromagnetic signals
US7465566B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 22, 2001 |
| Grant date | Dec 16, 2008 |
| Priority date | — |
| Expiry date | Oct 3, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and devices for the regulation of gene expression by cells via the application of fields generated by specific and selective electric and electromagnetic signals so as to target diseased or injured tissue for treatment. By gene expression is meant the up regulation or down regulation of the process whereby specific portions (genes) of the human genome (DNA) are transcribed into mRNA and subsequently translated into protein. Methods and devices are provided for the targeted treatment of injured or diseased tissue that include providing specific and selective electric and electromagnetic signals and exposing tissue to the fields generated by the signals so as to regulate gene expression. In particular, methods and devices are provided for the targeted treatment of bone defects, osteoarthritis, osteoporosis, cancer, and other disease states.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.