Patent · US Expired

Amide derivative

US7465748B2 · kind B2 · utility

0Cited by
5References
11Claims
0Family size

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Key dates

Filing dateAug 5, 2004
Grant dateDec 16, 2008
Priority date
Expiry dateAug 22, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There is provided a pharmaceutical drug, particularly a novel compound useful for prophylaxis or a therapeutic treatment of various diseases involving infections with viruses of the herpesvirus family, specifically various herpesvirus infections such as varicella (chicken pox) via varicella zoster virus, varicella zoster via recurrent infection with latent varicella zoster virus, herpes labialis and herpes encephalitis via HSV-1 and genital herpes via HSV-2 infection.An N-{2-[(4-substituted phenyl)amino]-2-oxoethyl}tetrahydro-2H-thiopyran-4-carboxamide derivative, of which phenyl group is substituted at position 4 with a specific 5- or 6-membered heteroaryl group, and a salt thereof have an effective anti-virus activity, and the oral administration thereof at a low dose enabled the therapeutic treatment of the above diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.