Patent · US Active

Letrozole purification process

US7465749B2 · kind B2 · utility

0Cited by

4References

21Claims

0Family size

Assignee

Chemagis Ltd. · IL

Inventors

Michal Hasson · Beer Sheva, IL
Hila Isenberg · Gdera, IL
Efrat Manoff · Rahat, IL
Moshe Bentolila · Afula, IL
Oded Friedman · Haifa, IL
Lior Zelikovitch · Mazkeret Batya, IL

Key dates

Filing date	Aug 3, 2006
Grant date	Dec 16, 2008
Priority date	—
Expiry date	Aug 3, 2026

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided is a process for purifying a letrozole product that contains an isoletrozole impurity, which process preferably includes converting at least a portion of the isoletrozole impurity into 4,4′-dicyanobenzophenone and removing 4,4′-dicyanobenzophenone, to produce a purified letrozole product.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.