System for controlling flow into chromatographic column using transfer line impedance
US7468095B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 2006 |
| Grant date | Dec 23, 2008 |
| Priority date | — |
| Expiry date | Jan 25, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/324
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the transfer line inlet pressure, determining the transfer line outlet pressure, and adjusting the applied pressure until the inlet and outlet pressures produce a desired flow rate for the transfer line outlet. In certain embodiments, the applied pressure is adjusted by controlling a proportional valve. In some embodiments, the outlet pressure is determined by measuring the pressure difference across the transfer line and calculating the transfer line outlet pressure from the measured inlet pressure and the pressure difference.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.