Cross-linked heparin coatings and methods
US7468210B1 · kind B1 · utility
20Cited by
41References
21Claims
0Family size
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Key dates
| Filing date | Dec 10, 2003 |
| Grant date | Dec 23, 2008 |
| Priority date | — |
| Expiry date | Oct 2, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31663
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A thromboresistant coating for a medical device, method of coating and coated medical device, the coating including an in situ cross-linked co-polymer of a cross-linkable biomolecule, preferably an adsorbable biomolecule such as a heparin activity biomolecule with at least one prosthetic hydrophobic unit, and a multifunctional crosslinking agent, such as a bis-variant of polyethylene glycol, polyethylene oxide, or polyethylene glycol, wherein the crosslinking is by means of covalent complexation through at least two functional groups of the multifunctional crosslinking agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.