Compositions comprising oxophosphonate-based metalloproteinase inhibitors
US7468359B2 · kind B2 · utility
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1References
8Claims
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Assignee
Inventors
Key dates
| Filing date | May 23, 2006 |
| Grant date | Dec 23, 2008 |
| Priority date | — |
| Expiry date | May 23, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions useful for treating or controlling disease states or conditions associated with zinc containing proteinases, especially metalloproteinases. The active ingredient in these compositions is an alpha-oxo- or alpha-thioxophosphonate of formula (I). Out of the phosphonates of formula (I), some are known and others are new. The novel compounds constitute another aspect of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.