Proteasome inhibitors and methods of using the same
US7468383B2 · kind B2 · utility
2Cited by
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22Claims
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Key dates
| Filing date | Feb 9, 2006 |
| Grant date | Dec 23, 2008 |
| Priority date | — |
| Expiry date | Nov 9, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly or indirectly with proteasome activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.