Microfluidic platform and method of generating a gradient therein
US7470403B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 26, 2006 |
| Grant date | Dec 30, 2008 |
| Priority date | — |
| Expiry date | Sep 29, 2026 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L3/5027
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
An apparatus and method of using the same are provided for generating a gradient of particles within a microfluidic device. The microfluidic device includes a channel having an input and an output. The channel is filled with a predetermined fluid. Thereafter, particles from a source pass through a porous membrane into the input of the channel. A second membrane is provided adjacent the output of the channel to minimize convection therein. A sink communicates with the output of the channel. The source/sink combination creates a pseudo-steady state in the channel wherein the concentration of particles at a point does not vary dramatically with time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.