Diphenylazetidinone derivatives for treating disorders of the lipid metabolism

US7470678B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Ingemar Starke · Gothenburg, SE
• Mikael Dahlstrom · Timrå, SE
• Ann-Margret Lindqvist · Timrå, SE
• Mats Peter Nordberg · Göteborg, SE
• Tore Skjaret · Hultsfred, SE
• Malin Lemurell · Mölndal, SE

Key dates

• Filing date: Jul 1, 2003
• Grant date: Dec 30, 2008
• Expiry date: Aug 24, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D205/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described