Compositions and methods related to modified retroviral vectors for restricted, site specific integration
US7470777B2 · kind B2 · utility
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6References
13Claims
0Family size
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Key dates
| Filing date | Dec 22, 2005 |
| Grant date | Dec 30, 2008 |
| Priority date | — |
| Expiry date | Dec 30, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16222
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Embodiments of the invention include compositions comprising and methods utilizing a retroviral integrase complex comprising a recombinant integrase having a domain comprising a non-native protein binding site, and a DNA binding protein comprising a DNA binding domain and a peptide binding domain that binds the non-native protein binding site of the recombinant integrase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.